RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
IFT80
RNA ID
RNA Type
circRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay; etc.
Target
CIRCRNA-0067835
Pathway
CIRCRNA-0067835; MIR-155; FOXO3
PubMed ID
Title
Thymosin-beta4 Mediates Hepatic Stellate Cell Activation by Interfering with CircRNA-0067835/miR-155/FoxO3 Signaling Pathway
Year
2018
Function
"Our experiments showed that circrna-0067835 regulated liver fibrosis progression by acting as a sponge of mir-155 to promote foxo3a expression, indicating that circrna-0067835 may serve as a potential therapeutic target for patients with liver fibrosis."